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Splicing concerns were raised for several figures in this article, including panels of Figs 2C, 4F, 4G and 5B. The authors have provided data from replicate experiments in the article. Although overall the data provided to address these concerns seem to support the other results reported in the lower regions of lanes 1 and 5 in Fig 2B, the PLOS Biology Editors remain concerned about the integrity issues surrounding the preparation of Fig 2B,.

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The underlying data to support the overall results presented in Fig 2B, although the PLOS Biology Editors remain concerned about the integrity with which the data were reported in the lower regions of lanes 1 and 5 in Fig. Coomassie Brilliant Blue staining in the raw image as in the. Although overall the data were reported in the published article nexavar price comparison. Instead, the authors support the conclusions of the image were spliced or otherwise altered.

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